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Merk: Beslutninger om behandling vurderes i fellesskap av forskriver og pasient underneath konsultasjonen. Den endelige avgjørelsen vil imidlertid alltid være forskriverens.In healthier male volunteers, there was no evidence of a clinically major outcome of azithromycin (500 mg every day for 3 times) over the systemic exposure of sildenafil or its significant circulating metabolite.
Although sildenafil enhances some markers of condition in people with pulmonary arterial hypertension, it does not look to have an effect on the risk of death or really serious Uncomfortable side effects.[20]
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Denne potenspillen er en behandling for menn som lider av erektil dysfunksjon (impotens) det vil si, manglende evne til å oppnå eller opprettholde en ereksjon som varer lenge nok for tilfredsstillende seksuell nytelse.
The necessarily mean profiles with the adjust from baseline in standing systolic hypertension in topics handled with doxazosin together with twenty five mg VIAGRA or matching placebo are proven in Determine 2.
Nosebleeds. Sildenafil may possibly cause nosebleeds. You may well be at increased threat for this if you are taking a blood thinner medicine. Convey to your healthcare service provider if you will get nosebleeds frequently when getting sildenafil. If your nosebleed is serious or will likely not prevent just after applying force, get assist instantly.
Physicians ought to recommend sufferers to prevent getting PDE5 inhibitors, like VIAGRA, and seek out prompt medical focus during the party of unexpected lessen or lack of hearing. These activities, which may be accompanied by tinnitus and dizziness, are already claimed in temporal association into the intake of PDE5 inhibitors, including VIAGRA.
Following both oral or intravenous administration, sildenafil is excreted as metabolites predominantly from the feces (around eighty% of administered oral dose) and to a lesser extent during the urine (somewhere around 13% in the administered oral dose).
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g., creatinine clearance < 30 mL/min), and concomitant utilization of erythromycin or sturdy CYP3A4 inhibitors, plasma levels of sildenafil at 24 several hours publish dose are actually discovered to become three to eight situations higher than Individuals seen in healthful volunteers. Though plasma amounts of sildenafil at 24 hours write-up dose are much decrease than at peak focus, it's not known no matter whether nitrates is usually securely co-administered presently position [see CONTRAINDICATIONS].
Injection Liquid. Sildenafil injection is usually presented by a Health care service provider inside of a hospital or clinic. You won't retail store get more info it in the home.
Although the interaction amongst other protease inhibitors and sildenafil has not been studied, their concomitant use is anticipated to increase sildenafil levels.
Even though exceptional, some individuals have described long-lasting eyesight reduction. Halt getting sildenafil and obtain support at once In case you have sudden eyesight reduction in one or both of those eyes.